ABSTRACT
Antisynthetase syndrome is a rare idiopathic inflammatory condition which is presented by Arthralgia, Myositis, Mechanic hands, unexplained fever, Raynaud's phenomenon, Anti- ARS (serum antibodies to aminocyl transfer RNA synthetases and ILD (Interstitial lung disease). This article will be all about the disease, causes, signs and symptoms, diagnosis and its herbal management.
INTRODUCTION
Antisynthetase syndrome is also known by the names of AS syndrome or Anti-jo1 syndrome. As every patient is different from other and unique in itself so all clinical features will not be present in every patient but yes group them will be seen.
Antisynthetase syndrome is a rare disorder which affects more women as compared to men and usually the people above 50 years of age have this disease. Some patients present initially or only with Interstitial lung disease (ILD) and worsening of ILD can result in increased mortality rate.
SIGNS AND SYMPTOMS
- Fever
- Shortness of breath
- Dysphagia
- Cough
- Weakness of proximal and axial muscles
- Stiffness of muscles
- Loss of appetite
- Weight loss
- Arthritis
- Arthralgia
- Esophageal dysmotility
- Erthyema on neck, shoulder, chest and back
- Pulmonary arterial hypertension
Clinical features in Antisynthetase syndrome may vary depending on time of appearance and severity. Main clinical features present are:
- Fever- This usually occurs at the initial stages of the disease and present in only around 20-30% of the patients. There can be continuous or intermittent fever.
- Inflammatory arthritis- Only the mild form is present in patients and around 50% or more patients suffer from this. Affects usually small joints of feet and hands and do not cause erosions of bones.
- Myositis- This is one of the most common feature present in more than 90% of patients. Patients affected from this have anti jo-antibodies in their stream. Complaints are difficulty in ascending stairs, getting up from bed and pain in muscles is usually seen. Shortness of breath is caused due to weakness of respiratory muscles.
- Mechanic’s hand- Only about 30% of patients get affected from this problem where thickening of skin occurs especially of finger tips. Name is given due to the appearance of hands like that of a mechanic.
- Lung disease- Most of the patients of Antisynthetase syndrome are affected from ILD and suffers from gradual appearance of shortness of breath. Dry cough can also be present and eventually pulmonary hypertension also develops.
- Raynaud’s phenomenon- 40% patients suffering from Antisynthetase syndrome develops Raynaud’s phenomenon. This is presented by reduction in blood supply to toes or fingers causing them to turn blue or red. Raynaud’s phenomenon is the response to sudden emotional stress or cold temperature.
CAUSES
Antisynthetase syndrome is a disorder of unknown origin. As immune system is found to be involved in its pathology hence is considered as a chronic autoimmune disease.
DIAGNOSIS
Presence of group of the clinical features discussed, points towards the Antisynthetase syndrome. However some investigations can confirm the diagnosis like Eclectromyography, MRI, Muscle biopsy, Lung function tests, CT scan, Lung biopsy and Muscle antibodies.
TREATMENT
In conservative mode of treatment Antisynthetase syndrome is treated depending upon the signs and symptoms present. Usually the Glucocorticosteroids are used in its treatment. As Antisynthetase syndrome is an autoimmune disease so the immunosuppresants are used to treat it which eventually expose a person to many ailments.
Side effects of the conservative treatment usually makes people to opt for a treatment which is natural, long term and without any side effects. Ayurveda is the answer to such treatment. Ayurveda is an alternative system of medicines which help in treating disease naturally.
HERBAL REMEDIES BY PLANET AYURVEDA
Planet Ayurveda is a well-known name in the field of Ayurveda worldwide. It is a herbal company which provides pure herbal medicines for the treatment of various disease, usually complex and chronic one. Medicines are prepared from best quality herbs following authentic Ayurvedic methods under the strict supervision of MD Ayurveda doctors. These herbal medicines are free from any type of chemicals, additives, preservatives, artificial colors etc. Genuineness of the herbs used in these herbal medicines increases the effectiveness of these medicines. For Antisynthetase syndrome also Planet Ayurveda offers a combination of herbal medicines that help in managing the condition naturally.
Herbal Remedies For Antisynthetase Syndrome
1. Giloy Capsules
These are the single herb capsules prepared from standardized extract of Tinospora cordifolia (Giloy). It possesses various medicinal properties like anti-inflammatory, antipyretic, antibacterial etc. Giloy capsules help in treating fever, muscle pains and enhance immunity as well.
Dosage - 1 capsule twice daily after meals with plain water.
2. Boswellia Curcumin
These herbal capsules are prepared from standardized extracts of Sallaki and active compound of turmeric, i.e. curcumin. Both these herbs together helps in treating pain, inflammation in muscles and joints, boost immunity, and provide relief from arthralgia, raynaud's phenomenon etc.
Dosage - Take 1 capsule twice daily after meals with plain water.
3. Manjishtha Capsules
Rubia cordifolia (Manjishtha) in a standardized extract form is used to prepare these amazing herbal capsules. It possesses therapeutic properties like anti-inflammatory and blood purifying which helps in treating complaints originating from Raynaud's phenomenon by improving blood supply and treating skin changes.
Dosage - Take 1 capsule twice daily after meals with plain water.
4. Yograj Guggul
These are the polyherbal tablets that are prepared from various herbs like Amla, Guggul, Long, Cinnamon, Sonth, Bibhitaki, Haritaki etc. These tablets possess anti inflammatory, anti tumor, analgesic etc. properties that helps in treating presenting complaints of Antisynthetase syndrome effectively. It also provides strength to the bones and prevents complaints like arthritis.
Dosage - Take 2 tablets twice daily after meals with plain water.
5. Spirulina Capsules
Spirulina capsules are prepared from the blue-green algae named Spirulina. These herbal capsules are full of minerals, vitamins and other healthy nutrients. It is a natural rich source of Vitamin B12 and other vitamins which helps in formation of hemoglobin and healthy red blood cells.
Dosage - Take 1 capsule twice daily after meals with plain water.
6. Vasaka Capsules
Vasaka capsules are single herb capsules prepared from standardized extract of Justicia adhatoda. It possesses many therapeutic properties like antibacterial, antifungal, bronchodilatory, anti asthmatic etc. All these properties helps in relieving difficult breathing, wheezing, cough and helps in treating respiratory allergies, asthma etc as well.
Dosage - Take 1 capsule twice daily after meals with plain water.
7. Aamvatantak Churna
This churna effectively treats conditions involving joints and muscles pain. It is a combination of various herbs like Ashwagandha, Haridra, Sonth, etc. This herbal churna helps in relieving pain and swelling of joints and muscles.
Dosage - Take 1 teaspoonful twice daily after meals with plain water.
8. Mahasudarshanghan Vati
This herbal tablet is prepared from combination of various medicinally amazing herbs like Haritaki, Daruhaldi, Kachur, Sonth, Kali mirch, Amla, Bibhitaki etc. They help in treating fever of various origins naturally. It also improves associated com plaints of fever like heaviness in abdomen, indigestion, loss of appetite and pain in body.
Dosage - Take 2 tablets twice daily after meals with plain water.
Contact my assistant to provide you the costing / ordering and delivery information at - costing.planetayurveda@gmail.com or call at +91-172-5214030 Or Check Website - www.PlanetAyurveda.com
CONCLUSION
Herbal medicines can be the safest and most effective way to treat an autoimmune condition like Antisynthetase syndrome naturally. These herbal medicines do provide long lasting effects without posing any side effects to an individual body system even if taken for long term. Hence natural is always best option to go for.
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