DO YOU KNOWN ABOUT DYSFERLINOPATHY?
Dysferlinopathy comes under category of musculoskeletal diseases. It is an autosomal recessive neuromuscular disorder caused by deficiency of functional dysferlin protein due to mutations in dysferlin gene. This disease is characterized by progressive muscle wasting. The exact cause of this disease is not known as it is rare disease. Dysferlinopathy is most commonly diagnosed as Limb-girdle muscular dystrophy type 2B (LGMD2B) or Miyoshi muscular dystrophy 1.This disease occur in early adulthood between age of 16 and 25 that affects skeletal muscle of limbs and limb girdles.
As per Ayurveda for a healthy body three doshas- vata, pitta and kapha are required in balance state. When there is increase in vata dosha along with "Mamsa dhatu" (muscles) basic body structure, it leads to muscle destruction. These are cause of formation of Dysferlinopathy.
WHAT ARE THE TYPES OF DYSFERLINOPATHY?
Some patients have no symptoms, others feel severe functional disability. There are two types of Dysferlinopathy that shows various symptoms as per the condition:
- Miyoshi myopathy
- Limb-girdle muscular dystrophy type 2B
WHAT ARE THE SYMPTOMS OF DYSFERLINOPATHY?
As per two types of Dysferlinopathy there are different symptoms appear according to conditions. These symptoms are mentioned below:
1. Symptoms According To Miyoshi Myopathy
- It causes wasting and weakness of muscles.
- Early symptoms appear in calf muscles of legs.
- Sometimes it is difficult for patients stand on tiptoe.
- With progression of disease muscle weakness and atrophy spreads to the thighs, gluteal muscles, shoulder girdle muscles and forearm.
- Few additional symptoms like difficulty in climbing stairs, walking, standing and decrease in grip strength.
2. Symptoms According To Limb-Girdle Muscular Dystrophy Type 2B:
- The muscles in the shoulder and pelvic girdle are more affected.
- Difficulty in running, climbing, walking and standing.
- Sometimes patient feel difficulty in doing activities that require the arms to be raised like combing hair.
DIAGNOSIS OF DYSFERLINOPATHY
For diagnosis of Dysferlinopathy genetic diagnosis is important. Routine blood investigation, CK level, conventional needle electromyography, electrocardiography, 2D electrocardiogram should be performed.
AYURVEDIC TREATMENT FOR DYSFERLINOPATHY
Ayurveda is best way to cure any disease either it is acute, chronic or related to genetic factors. So here are some combination of herbal remedy offered by Planet Ayurveda. These remedies will balance doshas, dhatus and symptoms related to Dysferlinopathy.
PRODUCTS LIST
- Brahmi Capsules
- Gotukola Capsules
- Atirasadi Churna
- Draksha Avleh
- Immune Booster Capsules
PRODUCTS DESCRIPTION
1. Brahmi Capsules
Pure extract of herb brahmi (Bacopa monnieri) is used for capsule formation. 100% natural high quality extract of potent brahmi plant is used. It has been used since ancient time for its medicinal value. Bacosides an active compound of Brahmi provide effective results in Dysferlinopathy disorder. The herb possesses anti-inflammatory, antioxidant, anti-depressant and anti-anxiety properties. These properties deal with symptoms related to this disorder. The capsules are used for rejuvenating nervous system, increases energy, strength and memory of an individual. It maintains overall health and wealth of human-beings.
Recommended Dosage: 1 capsule twice daily with plain water after meals.
2. Gotukola Capsules
These capsules contain 100% pure extract of herb Gotukola (Centella asiatica). This herb shows an effective therapeutic value from ancient time. As Dysferlinopathy is musculoskeletal disorder, consumption of these capsule boost confidence, improves memory, prevents nervous exhaustion, reduce stress and anxiety. It supports healthy blood circulation, maintain healthy brain and metabolism. The capsule balances all three doshas (vata, pitta and kapha) in body. Gotukola capsules cure muscle weakness, tiredness, fatigue, frustration and lack of energy. Regular use of these capsules overcome symptoms associated with Dysferlinopathy.
Recommended Dosage: 1 capsule twice daily with plain water after meals.
3. Ashwagandha Capsules
These capsules are prepared by standardized root extract of "Withania somnifera" herb. This herb is a rich in natural alkaloids having properties of stress relief, anxiety relief, improving stress, relieves tiredness. Routine use of this capsule relieves muscle spasm, fatigue, strength back muscles and calms down the system.
Recommended Dosage: 1 capsule twice daily with plain water after meals.
4. Atirasadi Churna
Atirasadi churna is an Ayurvedic formulation used for low stamina and energy level in the body. The herbs used for preparation of this churna are Safed musli (Chlorophytum borivilianum), Kali musli (Curculigo orchioides), Gokshur (Tribulus terrestris), Shatavari (Asparagus racemosus), Ashwagandha (Withania somnifera), Javitri (Myristica fragrans), Kesar (Crocus sativus) and Varahi kand (Pueraria tuberosa) etc.
- Safed Musli (Chlorophytum Borivilianum): This herb deals with symptoms related to this Dysferlinopathy.
- Kali Musli (Curculigo Orchioides): It is a rich source of micro-nutrients and anti-oxidants that restores energy and stamina.
- Gokshur (Tribulus Terrestris): This is a most common herb used to increase weakness, stamina, fatigue and anxiety.
- Shatavari (Asparagus Racemosus): This herb is used from ancient time for medicinal value. It will increase muscular strength and stamina.
- Ashwagandha (Withania Somnifera): The herb shows very effective result in Dysferlinopathy symptoms.
Recommended Dosage: 1 teaspoonful twice daily with plain water after meals.
5. Draksha Avaleha
This is one of the wonderful medicine for maintaining overall health of an individual. It gives effective results in associated symptoms of Dysferlinopathy. For preparation of this herb ingredients used are Draksha (Vitis vinifera), Tejpatra (Cinnamon tamala), Jatiphal (Mystrica fragrance), Ela (Elettaria cardamom) and Lavanga (Syzgium aromaticum) etc. It builds up muscular strength in body.
Recommended Dosage: Take 1 teaspoonful twice daily.
6. Immune Booster Capsules
These capsules are wonderful remedy which builds and enhances whole immune system rapidly. 100% pure organic compounds are used for capsules preparation. It helps to remove toxins, provides muscular strength, boost immune system and protects from infections. The capsules easily overcomes symptoms related to Dysferlinopathy. Ingredients used for preparation of these capsule are Grape seed (Vitis vinifera), Go-Piyush (Bovine colostrum), Bhumiamla (Phyllanthus niruri) and Amalaki (Emblica officinalis).
- Grape Seed (Vitis Vinifera): It helps to enhance immune system and maintains health.’
- Cow Colostrum (Bovine Colostrum): This builds up healthy muscles in body and maintain immune system. It is rich source of vitamins, minerals, proteins and micronutrients.
- Bhumi Amla (Phyllanthus Niruri): The herb act as a strong antioxidant property. Enhances overall health of an individual.
- Amalaki (Emblica Officinalis): This herb is rich source of vitamin C, minerals and nutrients. It balances all three doshas, builds a strong immune system and maintain a healthy body.
Recommended Dosage: 1 capsule twice daily with plain water after meals.
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