Retroperitoneal Fibrosis is a disease characterised by the presence of inflammation and fibrosis in the retroperitoneal space. The disease process begins with the symptoms like - flank pain and unexplained weight loss. The inflammation starts surrounding the large artery known as - aorta that delivers blood from the heart to the rest of the body at the level just below the kidneys and progresses inferiorly towards the arteries that carry blood to the legs and outward towards the kidneys and surrounding structures ultimately leading to kidney failure. If the inflammation surrounds the ureter leading from kidney to bladder and blocks the flow of urine, this can cause kidney to fail. It is previously described as chronic periaortitis. It is a rare fibrotic reaction in the retroperitoneum that typically presents with ureteral obstruction. It is characterised by the development of extensive fibrosis throughout the retro peritoneum which are centred over the anterior surface of the 4th and 5th lumbar vertebrae resulting in obstruction of retroperitoneal structures, most notably the uterus. There is currently no treatment for peritoneal fibrosis in modern medicine because no controlled therapeutic trials have been performed. Optimal care in patients with RPF requires an integrated approach of surgical and non-surgical therapies. Modern medicine prescribes medicines like - glucocorticoids, immunosuppressive agents, estrogen receptor antagonists but the best way to treat retroperitoneal fibrosis is not known to the modern physicians.
WHAT ARE THE SYMPTOMS OF RETROPERITONEAL FIBROSIS?
- Poorly localised, dull pain in the back or in the lower abdomen.
- Low extremity edema
- Fever
- weight loss
- Nausea
- Vomiting
- Anorexia
- Deep venous thrombosis
- Ureteric colic
This can also be associated with Crohn disease, ulcerative colitis, etc.
DIAGNOSIS
The diagnosis of retroperitoneal fibrosis requires a high degree of suspicion. Examination in patients with retroperitoneal fibrosis includes the following findings:
- Hypertension: Present in 50% of affected individuals with RPF.
- Occasionally abdominal mass is present.
- Obstruction of the ureters with varying degree of renal insufficiency. It is the earliest and most common organ involved.
Laboratory tests for patients with RPF include the following
- Erythrocyte Sedimentation Rate (ESR)
- C-Reactive Protein
- Urine and Creatinine tests
- Complete blood count
- Alkaline phosphate levels
- Anti-nuclear antibody levels
- Urinalysis
Imaging tests:
- Plain chest and abdominal radiography
- Abdominal MRI
- Kidney ultrasonography
- Abdominal CT scanning
WHAT ARE THE RISK FACTORS OF RETROPERITONEAL FIBROSIS?
- Actinomycosis (Bacterial Infection)
- Tuberculosis
- Abdominal tumors
- Occurs between the age group of 40-60 years
- External beam radiation used in cancer treatment
- Recent trauma of the abdomen or pelvis
RETROPERITONEAL FIBROSIS ACCORDING TO AYURVEDA
According to Ayurveda, this condition results due to the impairment of Vata and Pitta doshas in the body along with the impairment of body tissues. Ayurvedic herbs are quite helpful in this condition as they are a natural detoxifier and diuretic. This condition starts when inflammation and fibrosis of the abdominal aorta occurs. When the disease progresses, it starts affecting the arteries that carry blood to the legs as well as to the kidneys.
PLANET AYURVEDA'S HERBAL PRODUCTS FOR RETROPERITONEAL FIBROSIS:
1. Rencure Formula
Rencure formula of Planet Ayurveda is a herbal remedy which is prepared by the combination of herbs described in ancient texts as an effective herbal remedy for the diseases related to kidneys, thus Rencure Formula of Planet Ayurveda is very effective in the treatment of rectoperitoneal fibrosis.
Dosage: 1-2 capsule in the morning and evening with plain water after meals.
2. Punarnava Mandoor
This is the most common and most effective medicine used in Ayurvedic practice. It is a herbal remedy for decreasing urea/creatinine levels, swelling, puffy eyes, fluid accumulation and other endotoxins accumulation. It is a diuretic and widely used in the treatment of various renal disorders.
Dosage: 2 tablets twice daily with plain water after meals.
3. Varunadi Vati
Varunadi Vati of Planet Ayurveda is prepared from Varun herb. The best quality of Varun (Crataeva nirvala) is taken for its production. The regular use of Ayurvedic medicine Varunadi Vati helps to reduce toxins accumulated due to the improper functioning of the kidneys. This Ayurvedic product works wonderfully on the kidneys thus suitable for the treatment of rectoperitoneal fibrosis.
Dosage: 2 tablets twice daily with plain water after meals.
4. Kaishore Guggul
Ayurvedic product Kaishor Guggul contains the natural purifying herbs like - Triphala, Giloy, Guggul (resin). These herbs work as nature's best supplement to detox. It removes toxins from the blood and it is a useful herbal remedy for all metabolic disorders. It is particularly helpful for the accumulation of Pitta in the joints and muscles which may be indicated by pain and inflammation.
Dosage: 2 tablets twice a day with plain water after meals.
5. Phyllanthus Niruri Capsules
Phyllanthus niruri has hepatotoxic property. Phyllanthus niruri capsules are widely recommended to enhance the function of diseased liver. Phyllanthus niruri capsules of Planet Ayurveda contains the standardised extract of the plant - Bhumyamlaki or Bhumiamla. The word "Bhumi" means earth and "Amla" means small berries. This plant is considered acrid, cooling and alexipharmic. These capsules of Planet Ayurveda are useful in urinary problems, liver disorders with diuretic actions, and also improve immunity. It alleviates Kapha and Pitta doshas.
Dosage: 1 capsule twice daily with plain water with meals.
Rectoperitoneal Fibrosis Medicines at Planet Ayurveda are well researched and carefully designed by the expert team of Planet Ayurveda by understanding the pathophysiology of the disease thus saving the patient from kidney failure. Nature has the solution for all the problems and India has been blessed with rich heritage and traditional knowledge about herbal medicines. India exhibits a huge biodiversity with more than 25,000 herbal formulations being prescribed by more than a million practitioners relying on traditional medicines to cure the diseases. Ayurveda being practiced for thousands of years has reference to the safety and efficacy of individual drugs in classical texts. Ayurveda primarily focus on the synergistic effect of multiple ingredients, unlike the dependence on single Active Pharmaceutical Ingredient (API) in their modern counterpart. Ayurveda works on the root cause of the disease. Ayurveda does not believe in providing just symptomatic relief.
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